Structure of PDB 2q7i Chain A Binding Site BS01
Receptor Information
>2q7i Chain A (length=241) Species:
9606
(Homo sapiens) [
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PIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAK
ALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVF
NEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDG
LKNQKFFDELRMNYIKELDRIISCSRRFYQLTKLLDSVQPIARELHQFTF
DLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHTQ
Ligand information
>2q7i Chain B (length=10) Species:
9606
(Homo sapiens) [
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GAFQNLFQSV
Receptor-Ligand Complex Structure
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PDB
2q7i
Modulation of androgen receptor activation function 2 by testosterone and dihydrotestosterone.
Resolution
1.87 Å
Binding residue
(original residue number in PDB)
V716 K720 Q733 M734 I737 Q738 E893 M894 E897
Binding residue
(residue number reindexed from 1)
V46 K50 Q63 M64 I67 Q68 E215 M216 E219
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:2q7i
,
PDBe:2q7i
,
PDBj:2q7i
PDBsum
2q7i
PubMed
17591767
UniProt
P10275
|ANDR_HUMAN Androgen receptor (Gene Name=AR)
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