Structure of PDB 2q6j Chain A Binding Site BS01
Receptor Information
>2q6j Chain A (length=242) Species:
9606
(Homo sapiens) [
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LALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELV
HMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFA
PNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLN
SGVYTSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQL
LLILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHRL
Ligand information
>2q6j Chain C (length=10) Species:
10090
(Mus musculus) [
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KILHRLLQDS
Receptor-Ligand Complex Structure
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PDB
2q6j
Elemental isomerism: a boron-nitrogen surrogate for a carbon-carbon double bond increases the chemical diversity of estrogen receptor ligands
Resolution
2.7 Å
Binding residue
(original residue number in PDB)
I358 K362 V376 L539 E542 M543
Binding residue
(residue number reindexed from 1)
I53 K57 V71 L232 E235 M236
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:2q6j
,
PDBe:2q6j
,
PDBj:2q6j
PDBsum
2q6j
PubMed
17584613
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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