Structure of PDB 2pyj Chain A Binding Site BS01

Receptor Information
>2pyj Chain A (length=567) Species: 10756 (Salasvirus phi29) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PRKMYSCAFETTTKVEDCRVWAYGYMNIEDHSEYKIGNSLDEFMAWVLKV
QADLYFHNLKFAGAFIINWLERNGFKWSADGLPNTYNTIISRMGQWYMID
ICLGYKGKRKIHTVIYDSLKKLPFPVKKIAKDFKLTVLKGDIDYHKERPV
GYKITPEEYAYIKNDIQIIAEALLIQFKQGLDRMTAGSDSLKGFKDIITT
KKFKKVFPTLSLGLDKEVRYAYRGGFTWLNDRFKEKEIGEGMVFDVNSLY
PAQMYSRLLPYGEPIVFEGKYVWDEDYPLHIQHIRCEFELKEGYIPTIQI
KRSRFYKGNEYLKSSGGEIADLWLSNVDLELMKEHYDLYNVEYISGLKFK
ATTGLFKDFIDKWTYIKTTSEGAIKQLAKLMLNSLYGKFASNPDVTGKVP
YLKENGALGFRLGEEETKDPVYTPMGVFITAWARYTTITAAQACYDRIIY
CDTDSIHLTGTEIPDVIKDIVDPKKLGYWAHESTFKRAKYLRQKTYIQDI
YMKEVVEGSPDDYTDIKFSVKCAGMTDKIKKEVTFENFKVGFSRKMKPKP
VQVPGGVVLVDDTFTIK
Ligand information
Receptor-Ligand Complex Structure
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PDB2pyj Structures of phi29 DNA polymerase complexed with substrate: the mechanism of translocation in B-family polymerases
Resolution2.03 Å
Binding residue
(original residue number in PDB)		K64 K402 T457 K498 Y500 K529 C530 A531 G532 M533 K538
Binding residue
(residue number reindexed from 1)		K60 K398 T453 K494 Y496 K521 C522 A523 G524 M525 K530
Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
3.1.11.-
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0001882 nucleoside binding
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0004527 exonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0006260 DNA replication
GO:0039693 viral DNA genome replication

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Molecular Function
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Biological Process
External links
PDB RCSB:2pyj, PDBe:2pyj, PDBj:2pyj
PDBsum2pyj
PubMed17611604
UniProtP03680|DPOL_BPPH2 DNA polymerase (Gene Name=2)

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