Structure of PDB 2pvo Chain A Binding Site BS01

Receptor Information
>2pvo Chain A (length=110) Species: 1143 (Synechocystis sp.) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NKTLAAMKNFAEQYAKRTDTYFCSDLSVTAVVIEGLARHKEELGSPLCPC
RHYEDKEAEVKNTFWNCPCVPMRERKECHCMLFLTPDNDFAGDAQDIPME
TLEEVKASMA
Ligand information
Ligand IDSF4
InChIInChI=1S/4Fe.4S
InChIKeyLJBDFODJNLIPKO-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 2.0.7[S]12[Fe]3[S]4[Fe]1[S]5[Fe]2[S]3[Fe]45
CACTVS 3.385S1[Fe]S[Fe]1.S2[Fe]S[Fe]2
FormulaFe4 S4
NameIRON/SULFUR CLUSTER
ChEMBL
DrugBank
ZINC
PDB chain2pvo Chain A Residue 300 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2pvo Structural snapshots along the reaction pathway of ferredoxin-thioredoxin reductase.
Resolution3.4 Å
Binding residue
(original residue number in PDB)		C55 C74 C76 M79 C85 C87 F90
Binding residue
(residue number reindexed from 1)		C48 C67 C69 M72 C78 C80 F83
Annotation score1
Enzymatic activity
Enzyme Commision number 1.8.7.2: ferredoxin:thioredoxin reductase.
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0009055 electron transfer activity
GO:0016491 oxidoreductase activity
GO:0016730 oxidoreductase activity, acting on iron-sulfur proteins as donors
GO:0046872 metal ion binding
GO:0051539 4 iron, 4 sulfur cluster binding
GO:0103012 ferredoxin-thioredoxin reductase activity
Biological Process
GO:0015979 photosynthesis

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Molecular Function
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Biological Process
External links
PDB RCSB:2pvo, PDBe:2pvo, PDBj:2pvo
PDBsum2pvo
PubMed17611542
UniProtQ55389|FTRC_SYNY3 Ferredoxin-thioredoxin reductase, catalytic chain (Gene Name=ftrC)

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