Structure of PDB 2pkl Chain A Binding Site BS01

Receptor Information
>2pkl Chain A (length=249) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWA
KALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLV
FNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVD
GLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQPI
ARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHT
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2pkl A surface on the androgen receptor that allosterically regulates coactivator binding.
Resolution2.49 Å
Binding residue
(original residue number in PDB)
K720 Q733 M734 E893 M894
Binding residue
(residue number reindexed from 1)
K51 Q64 M65 E224 M225
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:2pkl, PDBe:2pkl, PDBj:2pkl
PDBsum2pkl
PubMed17911242
UniProtP10275|ANDR_HUMAN Androgen receptor (Gene Name=AR)

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