Structure of PDB 2pie Chain A Binding Site BS01
Receptor Information
>2pie Chain A (length=132) Species:
9606
(Homo sapiens) [
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GAHMAGGRSWCLRRVGMSAGWLLLEDGCEVTVGRGFGVTYQLVSKICPLM
ISRNHCVLKQNPEGQWTIMDNKSLNGVWLNRARLEPLRVYSIHQGDYIQL
GVPLENKENAEYEYEVTEEDWETIYPCLSPKN
Ligand information
>2pie Chain F (length=7) [
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ELKTERY
Receptor-Ligand Complex Structure
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PDB
2pie
RNF8 Transduces the DNA-Damage Signal via Histone Ubiquitylation and Checkpoint Protein Assembly.
Resolution
1.35 Å
Binding residue
(original residue number in PDB)
R42 C55 L57 M58 S60 R61 L82 N83
Binding residue
(residue number reindexed from 1)
R34 C47 L49 M50 S52 R53 L74 N75
Enzymatic activity
Enzyme Commision number
2.3.2.27
: RING-type E3 ubiquitin transferase.
External links
PDB
RCSB:2pie
,
PDBe:2pie
,
PDBj:2pie
PDBsum
2pie
PubMed
18001825
UniProt
O76064
|RNF8_HUMAN E3 ubiquitin-protein ligase RNF8 (Gene Name=RNF8)
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