Structure of PDB 2pc6 Chain A Binding Site BS01

Receptor Information

>2pc6 Chain A (length=164) Species: 228410 (Nitrosomonas europaea ATCC 19718) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

HMRHIISLLMENEAGALSRVAGLFSARGYNIESLSVAPTEDPTLSRMTLV
TNGPDEIVEQITKQLNKLIEVVKLIDLSSEGYVERELMLVKVRAVGKDRE
EMKRLADIFRGNIIDVTNELYTIELTGTRSKLDGFLQAVDCNLILEIART
GVSGLSRGERVLKL

Ligand information

Ligand ID

InChI

InChI=1S/Ca/q+2

InChIKey

BHPQYMZQTOCNFJ-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Ca++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Ca+2]

Formula

Name

CALCIUM ION

PDB chain

2pc6 Chain A Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	2pc6 Crystal structures of TM0549 and NE1324--two orthologs of E. coli AHAS isozyme III small regulatory subunit.
Resolution	2.5 Å
Binding residue (original residue number in PDB)	N65 L67 V70
Binding residue (residue number reindexed from 1)	N66 L68 V71
Annotation score	1

Enzymatic activity

Enzyme Commision number

2.2.1.6: acetolactate synthase.

Gene Ontology

	Molecular Function
GO:0003984	acetolactate synthase activity
GO:0016740	transferase activity
GO:0016829	lyase activity
GO:0046872	metal ion binding
GO:1990610	acetolactate synthase regulator activity

	Biological Process
GO:0008652	amino acid biosynthetic process
GO:0009082	branched-chain amino acid biosynthetic process
GO:0009097	isoleucine biosynthetic process
GO:0009099	L-valine biosynthetic process

	Cellular Component
GO:0005829	cytosol

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Cellular Component

External links

PDB	RCSB:2pc6, PDBe:2pc6, PDBj:2pc6
PDBsum	2pc6
PubMed	17586771
UniProt	Q82UZ2

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