Structure of PDB 2p5w Chain A Binding Site BS01
Receptor Information
>2p5w Chain A (length=276) Species:
9606
(Homo sapiens) [
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GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGQEQRYTCHVQHEGLPKPLTLRWEP
Ligand information
>2p5w Chain C (length=9) Species:
9606
(Homo sapiens) [
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SLLMWITQC
Receptor-Ligand Complex Structure
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PDB
2p5w
Crystal structures of high affinity human T-cell receptors bound to peptide major histocompatibility complex reveal native diagonal binding geometry
Resolution
2.2 Å
Binding residue
(original residue number in PDB)
Y7 F9 E63 K66 V67 H70 T73 V76 D77 L81 Y84 R97 Y99 T143 W147 V152 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 F9 E63 K66 V67 H70 T73 V76 D77 L81 Y84 R97 Y99 T143 W147 V152 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:2p5w
,
PDBe:2p5w
,
PDBj:2p5w
PDBsum
2p5w
PubMed
17644531
UniProt
P04439
|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)
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