Structure of PDB 2p0f Chain A Binding Site BS01

Receptor Information
>2p0f Chain A (length=119) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SHEVEKSGLLNMTKIAQGGRKLRKNWGPSWVVLTGNSLVFYREPPPTAPS
SGWGPAGSRPESSVDLRGAALAHGRHLSSRRNVLHIRTIPGHEFLLQSDH
ETELRAWHRALRTVIERLV
Ligand information
Ligand IDPO4
InChIInChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-3
InChIKeyNBIIXXVUZAFLBC-UHFFFAOYSA-K
SMILES
SoftwareSMILES
CACTVS 3.341[O-][P]([O-])([O-])=O
ACDLabs 10.04[O-]P([O-])([O-])=O
OpenEye OEToolkits 1.5.0[O-]P(=O)([O-])[O-]
FormulaO4 P
NamePHOSPHATE ION
ChEMBL
DrugBankDB14523
ZINC
PDB chain2p0f Chain A Residue 101 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2p0f Non-canonical Interaction of Phosphoinositides with Pleckstrin Homology Domains of Tiam1 and ArhGAP9.
Resolution1.91 Å
Binding residue
(original residue number in PDB)		K343 W345 S397 S398 R399
Binding residue
(residue number reindexed from 1)		K24 W26 S78 S79 R80
Annotation score3
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:2p0f, PDBe:2p0f, PDBj:2p0f
PDBsum2p0f
PubMed17339315
UniProtQ9BRR9|RHG09_HUMAN Rho GTPase-activating protein 9 (Gene Name=ARHGAP9)

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