Structure of PDB 2oof Chain A Binding Site BS01

Receptor Information
>2oof Chain A (length=403) Species: 32644 (unidentified) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LNCERVWLNVTPATLRSDLADYGLLEPHALGVHEGRIHALVPMQDLKYPA
HWQDMKGKLVTPGLIDCHTHLIFAGSRAEEFELRQKGVPYAEIARKGGGI
ISTVRATRAASEDQLFELALPRVKSLIREGVTTVEIKSGYGLTLEDELKM
LRVARRLGEALPIRVKTTLLAAHAVPPEYRDDPDSWVETICQEIIPAAAE
AGLADAVDVFCEHIGFSLAQTEQVYLAADQYGLAVKGHMDQLSNLGGSTL
AANFGALSVDHLEYLDPEGIQALAHRGVVATLLPTAFYFLKETKLPPVVA
LRKAGVPMAVSSDINPGTAPIVSLRMAMNMACTLFGLTPVEAMAGVTRHA
ARALGEQEQLGQLRVGMLADFLVWNCGHPAELSYLIGVDQLVSRVVNGEE
TLH
Ligand information
Ligand IDFE
InChIInChI=1S/Fe/q+3
InChIKeyVTLYFUHAOXGGBS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Fe+3]
FormulaFe
NameFE (III) ION
ChEMBL
DrugBankDB13949
ZINC
PDB chain2oof Chain A Residue 500 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2oof The crystal structure of 4-imidazolone-5-propanoate amidohydrolase from environmental sample
Resolution2.2 Å
Binding residue
(original residue number in PDB)		H72 H74 H242 D317
Binding residue
(residue number reindexed from 1)		H68 H70 H238 D313
Annotation score1
Enzymatic activity
Enzyme Commision number 3.5.2.7: imidazolonepropionase.
Gene Ontology
Molecular Function
GO:0005506 iron ion binding
GO:0008270 zinc ion binding
GO:0016787 hydrolase activity
GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GO:0046872 metal ion binding
GO:0050480 imidazolonepropionase activity
Biological Process
GO:0006547 L-histidine metabolic process
GO:0006548 L-histidine catabolic process
GO:0019556 L-histidine catabolic process to glutamate and formamide
GO:0019557 L-histidine catabolic process to glutamate and formate
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2oof, PDBe:2oof, PDBj:2oof
PDBsum2oof
PubMed
UniProtA0KF84|HUTI_AERHH Imidazolonepropionase (Gene Name=hutI)

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