Structure of PDB 2okl Chain A Binding Site BS01

Receptor Information
>2okl Chain A (length=185) Species: 226900 (Bacillus cereus ATCC 14579) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HMLTMKDVIREGDPILRNVAEEVSLPASEEDTTTLKEMIEFVINSQDPEM
AEKYSLRPGIGLAAPQIGVSKKMIAVHVTDADGTLYSHALFNPKIISHSV
ERTYLQGGEGCLSVDREVPGYVPRYTRITVKATSINGEEVKLRLKGLPAI
VFQHEIDHLNGVMFYDHINKENPFAAPDDSKPLER
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain2okl Chain A Residue 601 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB2okl Characterization of Peptide Deformylase2 from B. cereus
Resolution1.7 Å
Binding residue
(original residue number in PDB)		C110 H153 H157
Binding residue
(residue number reindexed from 1)		C111 H154 H158
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) G60 Q65 C110 L111 H153 E154 H157
Catalytic site (residue number reindexed from 1) G61 Q66 C111 L112 H154 E155 H158
Enzyme Commision number 3.5.1.88: peptide deformylase.
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
GO:0042586 peptide deformylase activity
GO:0046872 metal ion binding
Biological Process
GO:0006412 translation
GO:0043686 co-translational protein modification

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:2okl, PDBe:2okl, PDBj:2okl
PDBsum2okl
PubMed18047803
UniProtQ819K2|DEF2_BACCR Peptide deformylase 2 (Gene Name=def2)

[Back to BioLiP]