Structure of PDB 2o6m Chain A Binding Site BS01

Receptor Information
>2o6m Chain A (length=162) Species: 5791 (Physarum polycephalum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ALTNAQILAVIDSWEETVGQFPVITHHVPLGGGLQGTLHCYEIPLAAPYG
VGFAKNGPTRWQYKRTINQVVHRWGSHTVPFLLEPDNINGKTCTASQLCH
NTRCHNPLHLCWESLDDNKGRNWCPGPNGGCVHAVVCLRQGPLYGPGATV
AGPQQRGSHFVV
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2o6m Mutability of an HNH nuclease imidazole general base and exchange of a deprotonation mechanism.
Resolution2.3 Å
Binding residue
(original residue number in PDB)
A48 P49 G53 K56 N57 K65 T67
Binding residue
(residue number reindexed from 1)
A47 P48 G52 K55 N56 K64 T66
Binding affinityPDBbind-CN: Kd=13nM
Enzymatic activity
Catalytic site (original residue number in PDB) N119
Catalytic site (residue number reindexed from 1) N118
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
Biological Process
GO:0006314 intron homing

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Molecular Function

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Biological Process
External links
PDB RCSB:2o6m, PDBe:2o6m, PDBj:2o6m
PDBsum2o6m
PubMed17516660
UniProtQ94702|PPO1_PHYPO Intron-encoded endonuclease I-PpoI

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