Structure of PDB 2o5a Chain A Binding Site BS01

Receptor Information
>2o5a Chain A (length=108) Species: 86665 (Halalkalibacterium halodurans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SNQELLQLAVNAVDDKKAEQVVALNMKGISLDFFLICHGNSEKQVQAIAH
ELKKVAQEQGIEIKRLEGYEQARWVLIDLGDVVVHVFHKDERAYYNLEKL
WPTVELEG
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain2o5a Chain A Residue 127 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2o5a Crystal structure of Q9KD89 from Bacillus halodurans. Northeast Structural Genomics target BhR21
Resolution2.7 Å
Binding residue
(original residue number in PDB)		D35 D84
Binding residue
(residue number reindexed from 1)		D32 D81
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0043023 ribosomal large subunit binding
Biological Process
GO:0006417 regulation of translation
GO:0017148 negative regulation of translation
GO:0042256 cytosolic ribosome assembly
GO:0090071 negative regulation of ribosome biogenesis
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2o5a, PDBe:2o5a, PDBj:2o5a
PDBsum2o5a
PubMed
UniProtQ9KD89|IOJAP_HALH5 Ribosomal silencing factor RsfS (Gene Name=rsfS)

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