Structure of PDB 2lsk Chain A Binding Site BS01

Receptor Information

>2lsk Chain A (length=95) Species: 9606 (Homo sapiens)

GNLAGAVEFNDVKTLLREWITTISDPMEEDILQVVKYCTDLIEEKDLEKL
DLVIKYMKRLMQQSVESVWNMAFDFILDNVQVVLQQTYGSTLKVT

Ligand information

>2lsk Chain B (length=16) Species: 9606 (Homo sapiens)

QSTGTEPFFKQKSLLL

Receptor-Ligand Complex Structure

Structure summary

• PDB: 2lsk NMR structure and dynamics of the C-terminal domain from human Rev1 and its complex with Rev1 interacting region of DNA polymerase eta.
• Resolution: N/A
• Binding residue (original residue number in PDB): N1158 L1159 A1160 G1161 L1172 W1175 I1179 P1182 D1186 Q1189 V1190
• Binding residue (residue number reindexed from 1): N2 L3 A4 G5 L16 W19 I23 P26 D30 Q33 V34

Enzymatic activity

• Enzyme Commision number: 2.7.7.-

External links

• PDB: RCSB:2lsk, PDBe:2lsk, PDBj:2lsk
• PDBsum: 2lsk
• PubMed: 22691049
• UniProt: Q9UBZ9|REV1_HUMAN DNA repair protein REV1 (Gene Name=REV1)