Structure of PDB 2lgp Chain A Binding Site BS01

Receptor Information
>2lgp Chain A (length=94) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSPVLTCGPASFQCNSSTCIPQLWACDNDPDCEDGSDEWPQRCRGLYVFQ
GDSSPCSAFEFHCLSGECIHSSWRCDGGPDCKDKSDEENCAVAT
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain2lgp Chain A Residue 215 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2lgp The Structure, Dynamics, and Binding of the LA45 Module Pair of the Low-Density Lipoprotein Receptor Suggest an Important Role for LA4 in Ligand Release.
ResolutionN/A
Binding residue
(original residue number in PDB)		W144 D147 D149 D151 D157 E158
Binding residue
(residue number reindexed from 1)		W24 D27 D29 D31 D37 E38
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:2lgp, PDBe:2lgp, PDBj:2lgp
PDBsum2lgp
PubMed22091758
UniProtP01130|LDLR_HUMAN Low-density lipoprotein receptor (Gene Name=LDLR)

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