Structure of PDB 2leh Chain A Binding Site BS01

Receptor Information
>2leh Chain A (length=189) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GYSPTLQWQQQQVAQFSTVRQNVNKHRSHWKSQQLDSNVTMPKSEDEEGW
KKFCLGEKLCADGAVGPATNESPGIDYVQIGFPPLLSIVSRMNQATVTSV
LEYLSNWFGERDFTPELGRWLYALLACLEKPLLPEAHSLIRQLARRCSEV
RLLVDSKDDERVPALNLLICLVSRYFDQRDLADEPSLEY
Ligand information
>2leh Chain B (length=26) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
GQSDDSDIWDDTALIKAYDKAVASFK
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB2leh Solution structure of the core SMN-Gemin2 complex.
ResolutionN/A
Binding residue
(original residue number in PDB)		Q109 H120 H123 R213 Y216 P257
Binding residue
(residue number reindexed from 1)		Q15 H26 H29 R119 Y122 P163
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0000387 spliceosomal snRNP assembly

View graph for
Biological Process
External links
PDB RCSB:2leh, PDBe:2leh, PDBj:2leh
PDBsum2leh
PubMed22607171
UniProtO14893|GEMI2_HUMAN Gem-associated protein 2 (Gene Name=GEMIN2)

[Back to BioLiP]