Structure of PDB 2le8 Chain A Binding Site BS01

Receptor Information
>2le8 Chain A (length=114) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
APKASLRLGFSEYSRISNLIVLHLRKVEEEEDESALKRSELVNWYLKEIE
SEIDSEEELINKKRIIEKVIHRLTHYDHVLIELTQAGLKGSTEGSESYEE
DPYLVVNPNYLLED
Ligand information
>2le8 Chain B (length=29) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
SALKGVSQDLLERIRAKEAQKQLAQMTRW
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2le8 Structural insights into the Cdt1-mediated MCM2-7 chromatin loading
ResolutionN/A
Binding residue
(original residue number in PDB)		I57 D58 E60 L63 I64 K67 R68 E71
Binding residue
(residue number reindexed from 1)		I53 D54 E56 L59 I60 K63 R64 E67
Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
External links
PDB RCSB:2le8, PDBe:2le8, PDBj:2le8
PDBsum2le8
PubMed22140117
UniProtQ14566|MCM6_HUMAN DNA replication licensing factor MCM6 (Gene Name=MCM6)

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