Structure of PDB 2l6e Chain A Binding Site BS01
Receptor Information
>2l6e Chain A (length=94) Species:
11676
(Human immunodeficiency virus 1) [
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SGLVPRGSHMTSILDIRQGPKEPFRDYVDRFYKTLRAEQASQEVKNAATE
TLLVQNANPDCKTILKALGPAATLEEMMTACQGVGGPGHKARVL
Ligand information
>2l6e Chain B (length=14) [
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ITFLDLLLYYGKKK
Receptor-Ligand Complex Structure
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PDB
2l6e
Solution structure of a hydrocarbon stapled peptide inhibitor in complex with monomeric C-terminal domain of HIV-1 capsid.
Resolution
N/A
Binding residue
(original residue number in PDB)
V165 D166 Y169 L172 R173 N183 T186 E187 L211 E212 M215
Binding residue
(residue number reindexed from 1)
V28 D29 Y32 L35 R36 N46 T49 E50 L74 E75 M78
Enzymatic activity
Catalytic site (original residue number in PDB)
A194 L205 A208 A209 E213
Catalytic site (residue number reindexed from 1)
A57 L68 A71 A72 E76
Enzyme Commision number
2.7.7.-
2.7.7.49
: RNA-directed DNA polymerase.
2.7.7.7
: DNA-directed DNA polymerase.
3.1.-.-
3.1.13.2
: exoribonuclease H.
3.1.26.13
: retroviral ribonuclease H.
3.4.23.16
: HIV-1 retropepsin.
External links
PDB
RCSB:2l6e
,
PDBe:2l6e
,
PDBj:2l6e
PDBsum
2l6e
PubMed
18417468
UniProt
P35963
|POL_HV1Y2 Gag-Pol polyprotein (Gene Name=gag-pol)
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