Structure of PDB 2l3c Chain A Binding Site BS01

Receptor Information
>2l3c Chain A (length=74) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PGPVLPKNALMQLNEIKPGLQYMLLSQTGPVHAPLFVMSVEVNGQVFEGS
GPTKKKAKLHAAEKALRSFVQFPN
Ligand information
>2l3c Chain B (length=34) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gguaguauaacaauauccguguuguuauaguacc
<<<<.<<<<<<<<<<....>>>>>>>>>>.>>>>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB2l3c The Solution Structure of the ADAR2 dsRBM-RNA Complex Reveals a Sequence-Specific Readout of the Minor Groove.
ResolutionN/A
Binding residue
(original residue number in PDB)
K7 L10 M11 N14 E15 V31 H32 P34 T53 K54 K55 K58
Binding residue
(residue number reindexed from 1)
K7 L10 M11 N14 E15 V31 H32 P34 T53 K54 K55 K58
Binding affinityPDBbind-CN: Kd=330nM
Enzymatic activity
Enzyme Commision number 3.5.4.37: double-stranded RNA adenine deaminase.
External links
PDB RCSB:2l3c, PDBe:2l3c, PDBj:2l3c
PDBsum2l3c
PubMed20946981
UniProtP51400|RED1_RAT Double-stranded RNA-specific editase 1 (Gene Name=Adarb1)

[Back to BioLiP]