Structure of PDB 2kup Chain A Binding Site BS01
Receptor Information
>2kup Chain A (length=146) Species:
9606
(Homo sapiens) [
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GSSGSSGLNRDSVPDNHPTKFKVTNVDDEGVELGSGVMELTQSELVLHLH
RREAVRWPYLCLRRYGYDSNLFSFESGRRCQTGQGIFAFKCSRAEEIFNL
LQDLMQCNSINVMEEPVIITRNSHPAELDLPRAPQPPNALGYTVSS
Ligand information
>2kup Chain B (length=19) Species:
9606
(Homo sapiens) [
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LFRLRHFPCGNVNYGYQQQ
Receptor-Ligand Complex Structure
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PDB
2kup
Structural basis for the recognition of nucleophosmin-anaplastic lymphoma kinase oncoprotein by the phosphotyrosine binding domain of Suc1-associated neurotrophic factor-induced tyrosine-phosphorylated target-2
Resolution
N/A
Binding residue
(original residue number in PDB)
N25 D27 D28 Y59 L60 R64 Y65 G66 Y67 S73 F74 R79 I86 F87 F98 Q102 M105
Binding residue
(residue number reindexed from 1)
N25 D27 D28 Y59 L60 R64 Y65 G66 Y67 S73 F74 R79 I86 F87 F98 Q102 M105
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:2kup
,
PDBe:2kup
,
PDBj:2kup
PDBsum
2kup
PubMed
20454865
UniProt
O43559
|FRS3_HUMAN Fibroblast growth factor receptor substrate 3 (Gene Name=FRS3)
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