Structure of PDB 2krb Chain A Binding Site BS01

Receptor Information
>2krb Chain A (length=81) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DSVIVVDNVPQVGPDRLEKLKNVIHKIFSKFGKITNDFYPEEDGKTKGYI
FLEYASPAHAVDAVKNADGYKLDKQHTFRVN
Ligand information
Receptor-Ligand Complex Structure
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PDB2krb The indispensable N-terminal half of eIF3j/HCR1 co-operates with its structurally conserved binding partner eIF3b/PRT1-RRM and eIF1A in stringent AUG selection
ResolutionN/A
Binding residue
(original residue number in PDB)		K33 N36 V37 I38 K40 I41 G83 Y84 K85 L86 F92
Binding residue
(residue number reindexed from 1)		K19 N22 V23 I24 K26 I27 G69 Y70 K71 L72 F78
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0003743 translation initiation factor activity
GO:0031369 translation initiation factor binding
Biological Process
GO:0006413 translational initiation
Cellular Component
GO:0005852 eukaryotic translation initiation factor 3 complex

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Cellular Component
External links
PDB RCSB:2krb, PDBe:2krb, PDBj:2krb
PDBsum2krb
PubMed
UniProtP55884|EIF3B_HUMAN Eukaryotic translation initiation factor 3 subunit B (Gene Name=EIF3B)

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