Structure of PDB 2ko0 Chain A Binding Site BS01
Receptor Information
>2ko0 Chain A (length=87) Species:
9606
(Homo sapiens) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
MVQSCSAYGCKNRYDKDKPVSFHKFPLTRPSLCKEWEAAVRRKNFKPTKY
SSICSEHFTPDSFKRESNNKLLKENAVPTIFLELVPR
Ligand information
>2ko0 Chain B (length=16) [
Search DNA sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
gcttgtgtgggcagcg
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
2ko0
Structural determinants of specific DNA-recognition by the THAP zinc finger
Resolution
N/A
Binding residue
(original residue number in PDB)
M1 V2 Q3 Y14 F22 H23 K24 T28 K64 R65 L71
Binding residue
(residue number reindexed from 1)
M1 V2 Q3 Y14 F22 H23 K24 T28 K64 R65 L71
Binding affinity
PDBbind-CN
: Kd=480nM
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0043565
sequence-specific DNA binding
View graph for
Molecular Function
External links
PDB
RCSB:2ko0
,
PDBe:2ko0
,
PDBj:2ko0
PDBsum
2ko0
PubMed
20144952
UniProt
Q9NVV9
|THAP1_HUMAN THAP domain-containing protein 1 (Gene Name=THAP1)
[
Back to BioLiP
]