Structure of PDB 2kkh Chain A Binding Site BS01

Receptor Information
>2kkh Chain A (length=95) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ALQNKEEEKKKVKKLQKSYFDVLGICCTSEVPIIENILKSLDGVKEYSVI
VPSRTVIVVHDSLLISPFQIAKALNEARLEANVRVNGETSFKNKW
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain2kkh Chain A Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2kkh Metal binding affinities of Arabidopsis zinc and copper transporters: selectivities match the relative, but not the absolute, affinities of their amino-terminal domains
ResolutionN/A
Binding residue
(original residue number in PDB)		C27 C28 E31
Binding residue
(residue number reindexed from 1)		C26 C27 E30
Annotation score5
Enzymatic activity
Enzyme Commision number 7.2.2.12: P-type Zn(2+) transporter.
7.2.2.21: Cd(2+)-exporting ATPase.
Gene Ontology
Molecular Function
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:2kkh, PDBe:2kkh, PDBj:2kkh
PDBsum2kkh
PubMed19883117
UniProtO64474|HMA4_ARATH Putative cadmium/zinc-transporting ATPase HMA4 (Gene Name=HMA4)

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