Structure of PDB 2k7o Chain A Binding Site BS01

PDB	2k7o Refinement of the solution structure and dynamic properties of Ca(2+)-bound rat S100B.
Resolution	N/A
Binding residue (original residue number in PDB)	S18 E21 K26 E31
Binding residue (residue number reindexed from 1)	S18 E21 K26 E31
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0005102	signaling receptor binding
GO:0005509	calcium ion binding
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0042802	identical protein binding
GO:0042803	protein homodimerization activity
GO:0044548	S100 protein binding
GO:0046872	metal ion binding
GO:0048156	tau protein binding
GO:0048306	calcium-dependent protein binding
GO:0050786	RAGE receptor binding

	Biological Process
GO:0007155	cell adhesion
GO:0007611	learning or memory
GO:0007613	memory
GO:0008284	positive regulation of cell population proliferation
GO:0008360	regulation of cell shape
GO:0031643	positive regulation of myelination
GO:0043065	positive regulation of apoptotic process
GO:0043123	positive regulation of canonical NF-kappaB signal transduction
GO:0045666	positive regulation of neuron differentiation
GO:0048168	regulation of neuronal synaptic plasticity
GO:0048708	astrocyte differentiation
GO:0050806	positive regulation of synaptic transmission
GO:0051384	response to glucocorticoid
GO:0051597	response to methylmercury
GO:0060291	long-term synaptic potentiation
GO:0071456	cellular response to hypoxia
GO:0097490	sympathetic neuron projection extension
GO:1990138	neuron projection extension
GO:1990845	adaptive thermogenesis
GO:2001015	negative regulation of skeletal muscle cell differentiation

	Cellular Component
GO:0001726	ruffle
GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0043025	neuronal cell body
GO:0048471	perinuclear region of cytoplasm

External links

PDB	RCSB:2k7o, PDBe:2k7o, PDBj:2k7o
PDBsum	2k7o
PubMed	18949447
UniProt	P04631\|S100B_RAT Protein S100-B (Gene Name=S100b)