Structure of PDB 2k3w Chain A Binding Site BS01
Receptor Information
>2k3w Chain A (length=73) Species:
9606
(Homo sapiens) [
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TSTLQKAIDLVTKATEEDKAKNYEEALRLYQHAVEYFLHAIKYEAHSDKA
KESIRAKCVQYLDRAEKLKDYLR
Ligand information
>2k3w Chain B (length=12) Species:
9606
(Homo sapiens) [
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IELPEVPSEPLP
Receptor-Ligand Complex Structure
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PDB
2k3w
Two distinct modes of ESCRT-III recognition are required for VPS4 functions in lysosomal protein targeting and HIV-1 budding
Resolution
N/A
Binding residue
(original residue number in PDB)
T17 D20 K21 Y32 F39 A52 K59 Y63 R66 Y73
Binding residue
(residue number reindexed from 1)
T15 D18 K19 Y30 F37 A50 K57 Y61 R64 Y71
Enzymatic activity
Enzyme Commision number
3.6.4.6
: vesicle-fusing ATPase.
External links
PDB
RCSB:2k3w
,
PDBe:2k3w
,
PDBj:2k3w
PDBsum
2k3w
PubMed
18606141
UniProt
Q9UN37
|VPS4A_HUMAN Vacuolar protein sorting-associated protein 4A (Gene Name=VPS4A)
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