Structure of PDB 2k3r Chain A Binding Site BS01

Receptor Information
>2k3r Chain A (length=91) Species: 2261 (Pyrococcus furiosus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KERIDILFSLAERVFPYSPELAKRYVELALLVQQKAKVKIPRKWKRRYCK
KCHAFLVPGINARVRLRQKRMPHIVVKCLECGHIMRYPYIK
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain2k3r Chain A Residue 124 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB2k3r Solution structure of Pyrococcus furiosus RPP21, a component of the archaeal RNase P holoenzyme, and interactions with its RPP29 protein partner.
ResolutionN/A
Binding residue
(original residue number in PDB)		C63 C66 C92 C95
Binding residue
(residue number reindexed from 1)		C49 C52 C78 C81
Annotation score4
Enzymatic activity
Enzyme Commision number 3.1.26.5: ribonuclease P.
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0004526 ribonuclease P activity
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0001682 tRNA 5'-leader removal
GO:0006396 RNA processing
GO:0008033 tRNA processing
Cellular Component
GO:0005737 cytoplasm
GO:0030677 ribonuclease P complex
GO:1902555 endoribonuclease complex
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:2k3r, PDBe:2k3r, PDBj:2k3r
PDBsum2k3r
PubMed18922021
UniProtQ8U0H6|RNP4_PYRFU Ribonuclease P protein component 4 (Gene Name=rnp4)

[Back to BioLiP]