Structure of PDB 2jtg Chain A Binding Site BS01

Receptor Information
>2jtg Chain A (length=87) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MVQSCSAYGCKNRYDKDKPVSFHKFPLTRPSLCKEWEAAVRRKNFKPTKY
SSICSEHFTPDCFKRECNNKLLKENAVPTIFLELVPR
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain2jtg Chain A Residue 88 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2jtg Structure-function analysis of the THAP zinc finger of THAP1, a large C2CH DNA-binding module linked to Rb/E2F pathways
ResolutionN/A
Binding residue
(original residue number in PDB)		C5 C10 C54 H57
Binding residue
(residue number reindexed from 1)		C5 C10 C54 H57
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0043565 sequence-specific DNA binding

View graph for
Molecular Function
External links
PDB RCSB:2jtg, PDBe:2jtg, PDBj:2jtg
PDBsum2jtg
PubMed18073205
UniProtQ9NVV9|THAP1_HUMAN THAP domain-containing protein 1 (Gene Name=THAP1)

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