Structure of PDB 2jfa Chain A Binding Site BS01

Receptor Information
>2jfa Chain A (length=221) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLALSLTADQMVSALLDAEPPILYSEYPFSEASMMGLLTNLADRELVHMI
NWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNL
LLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGV
YTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLL
LILSHIRHMSNKGMEHLYSMK
Ligand information
>2jfa Chain P (length=15) Species: 32630 (synthetic construct) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
DAFQLRQLILRGLQD
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB2jfa Structural Insights Into Corepressor Recognition by Antagonist-Bound Estrogen Receptors.
Resolution2.55 Å
Binding residue
(original residue number in PDB)		L354 I358 K362 L372 Q375 E380
Binding residue
(residue number reindexed from 1)		L46 I50 K54 L64 Q67 E72
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:2jfa, PDBe:2jfa, PDBj:2jfa
PDBsum2jfa
PubMed17283072
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

[Back to BioLiP]