Structure of PDB 2jcc Chain A Binding Site BS01

Receptor Information
>2jcc Chain A (length=275) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEALRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGQEQRYTCHVQHEGLPKPLTLRWE
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2jcc Single Mhc Mutation Eliminates Enthalpy Associated with T Cell Receptor Binding.
Resolution2.5 Å
Binding residue
(original residue number in PDB)
Y7 E63 K66 V67 A69 H70 T73 D77 T80 L81 Y84 Y99 Y116 T143 K146 W147 Q155 L156 Y159
Binding residue
(residue number reindexed from 1)
Y7 E63 K66 V67 A69 H70 T73 D77 T80 L81 Y84 Y99 Y116 T143 K146 W147 Q155 L156 Y159
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:2jcc, PDBe:2jcc, PDBj:2jcc
PDBsum2jcc
PubMed17825839
UniProtP04439|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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