Structure of PDB 2j1n Chain A Binding Site BS01

Receptor Information

>2j1n Chain A (length=346) Species: 562 (Escherichia coli)

AEVYNKDGNKLDLYGKVDGLHYFSDNKDVDGDQTYMRLGFKGETQVTDQL
TGYGQWEYQIQGNSAENENNSWTRVAFAGLKFQDVGSFDYGRNYGVVYDV
TSWTDVLPEFGGDTYGSDNFMQQRGNGFATYRNTDFFGLVDGLNFAVQYQ
GKNGNPSGEGFTSGVTNNGRDALRQNGDGVGGSITYDYEGFGIGGAISSS
KRTDAQNTAAYIGNGDRAETYTGGLKYDANNIYLAAQYTQTYNATRVGSL
GWANKAQNFEAVAQYQFDFGLRPSLAYLQSKGKNLGRGYDDEDILKYVDV
GATYYFNKNMSTYVDYKINLLDDNQFTRDAGINTDNIVALGLVYQF

Ligand information

• Ligand ID: MG
• InChI: InChI=1S/Mg/q+2
• InChIKey: JLVVSXFLKOJNIY-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mg+2]
  CACTVS 3.341: [Mg++]
• Formula: Mg
• Name: MAGNESIUM ION
• DrugBank: DB01378
• PDB chain: 2j1n Chain A Residue 1347

Receptor-Ligand Complex Structure

Structure summary

• PDB: 2j1n Crystal Structure of Osmoporin Ompc from E. Coli at 2.0 A.
• Resolution: 2.0 Å
• Binding residue (original residue number in PDB): N319 L321 T334
• Binding residue (residue number reindexed from 1): N319 L321 T334
• Annotation score: 4

Gene Ontology

Molecular Function

• GO:0001618 virus receptor activity
• GO:0005515 protein binding
• GO:0015288 porin activity
• GO:0042802 identical protein binding
• GO:0046872 metal ion binding

Biological Process

• GO:0006811 monoatomic ion transport
• GO:0006974 DNA damage response
• GO:0034220 monoatomic ion transmembrane transport
• GO:0046718 symbiont entry into host cell
• GO:0046813 receptor-mediated virion attachment to host cell
• GO:0120010 intermembrane phospholipid transfer

Cellular Component

• GO:0009279 cell outer membrane
• GO:0016020 membrane
• GO:0046930 pore complex

External links

• PDB: RCSB:2j1n, PDBe:2j1n, PDBj:2j1n
• PDBsum: 2j1n
• PubMed: 16949612
• UniProt: P06996|OMPC_ECOLI Outer membrane porin C (Gene Name=ompC)