Structure of PDB 2iye Chain A Binding Site BS01

Receptor Information

>2iye Chain A (length=249) Species: 273057 (Saccharolobus solfataricus P2)

ALSLYEKMLHKGMIIKNSNVYEKIKEIDTIIFDKTGTLTYGTPIVTQFIG
DSLSLAYAASVEALSSHPIAKAIVKYAKEQGVKILEVKDFKEISGIGVRG
KISDKIIEVKKAEDIAVYINGEPIASFNISDVPRPNLKDYLEKLKNEGLK
IIILSGDKEDKVKELSKELNIQEYYSNLSPEDKVRIIEKLKQNGNKVLMI
GDGVNDAAALALADVSVAMGNGVDISKNVADIILVSNDIGTLLGLIKNR

Ligand information

• Ligand ID: SO4
• InChI: InChI=1S/H2O4S/c1-5(2,3)4/h(H2,1,2,3,4)/p-2
• InChIKey: QAOWNCQODCNURD-UHFFFAOYSA-L
• SMILES:
  OpenEye OEToolkits 1.5.0: [O-]S(=O)(=O)[O-]
  CACTVS 3.341: [O-][S]([O-])(=O)=O
  ACDLabs 10.04: [O-]S([O-])(=O)=O
• Formula: O4 S
• Name: SULFATE ION
• DrugBank: DB14546
• PDB chain: 2iye Chain A Residue 1636

Receptor-Ligand Complex Structure

Structure summary

• PDB: 2iye Sulfate Acts as Phosphate Analog on the Monomeric Catalytic Fragment of the Cpx-ATPase Copb from Sulfolobus Solfataricus
• Resolution: 2.6 Å
• Binding residue (original residue number in PDB): G542 K569 N591
• Binding residue (residue number reindexed from 1): G156 K183 N205
• Annotation score: 1

Enzymatic activity

• Catalytic site (original residue number in PDB): D416
• Catalytic site (residue number reindexed from 1): D33
• Enzyme Commision number: 3.6.3.10: Transferred entry: 7.2.2.19.

Gene Ontology

Molecular Function

• GO:0000166 nucleotide binding
• GO:0005215 transporter activity
• GO:0005524 ATP binding
• GO:0016887 ATP hydrolysis activity

Cellular Component

• GO:0016020 membrane

External links

• PDB: RCSB:2iye, PDBe:2iye, PDBj:2iye
• PDBsum: 2iye
• PubMed: 17434529
• UniProt: Q97UU7