Structure of PDB 2iwv Chain A Binding Site BS01

Receptor Information

>2iwv Chain A (length=277) Species: 83333 (Escherichia coli K-12)

NDWHFNIGAMYEIENVEGYGEDMDGLAEPSVYFNAANGPWRIALAYYQEG
PVDYSAGKRGTWFDRPELEVHYQFLENDDFSFGLTGGFRNYGYHYVDEPG
KDTANMQRWKIAPDWDVKLTDDLRFNGWLSMYKFANDLNTTGYADTRVET
ETGLQYTFNETVALRVNYYLERGFNMDDSRNNGEFSTQEIRAYLPLTLGN
HSVTPYTRIGLDRWSNWDWQDDIEREGHDFNRVGLFYGYDFQNGLSVSLE
YAFEWQDHDEGDSDKFHYAGVGVNYSF

Ligand information

• Ligand ID: CA
• InChI: InChI=1S/Ca/q+2
• InChIKey: BHPQYMZQTOCNFJ-UHFFFAOYSA-N
• SMILES:
  CACTVS 3.341: [Ca++]
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Ca+2]
• Formula: Ca
• Name: CALCIUM ION
• DrugBank: DB14577
• PDB chain: 2iwv Chain A Residue 1281

Receptor-Ligand Complex Structure

Structure summary

• PDB: 2iwv Structure of the Monomeric Outer-Membrane Porin Ompg in the Open and Closed Conformation.
• Resolution: 2.3 Å
• Binding residue (original residue number in PDB): N18 V19 G21 D25 M26
• Binding residue (residue number reindexed from 1): N15 V16 G18 D22 M23
• Annotation score: 1

Gene Ontology

Molecular Function

• GO:0015288 porin activity
• GO:0015478 oligosaccharide transporting porin activity
• GO:0015481 maltose transporting porin activity

Biological Process

• GO:0006811 monoatomic ion transport
• GO:0015768 maltose transport
• GO:0015772 oligosaccharide transport
• GO:0034219 carbohydrate transmembrane transport

Cellular Component

• GO:0009279 cell outer membrane
• GO:0046930 pore complex

External links

• PDB: RCSB:2iwv, PDBe:2iwv, PDBj:2iwv
• PDBsum: 2iwv
• PubMed: 16888630
• UniProt: P76045|OMPG_ECOLI Outer membrane porin G (Gene Name=ompG)