Structure of PDB 2iui Chain A Binding Site BS01
Receptor Information
>2iui Chain A (length=107) Species:
9606
(Homo sapiens) [
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MSLQNAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKG
GNNKLIKIFHRDGKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLL
YPVSKYQ
Ligand information
>2iui Chain C (length=11) Species:
9606
(Homo sapiens) [
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SIDYVPMLDMK
Receptor-Ligand Complex Structure
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PDB
2iui
Crystal Structure of the Pi 3-Kinase P85 Amino- Terminal Sh2 Domain and its Phosphopeptide Complexes
Resolution
2.4 Å
Binding residue
(original residue number in PDB)
R19 R37 S40 T48 L59 I60 K61 S72 D73 P74 Y95 N96 L99
Binding residue
(residue number reindexed from 1)
R15 R33 S36 T44 L55 I56 K57 S68 D69 P70 Y91 N92 L95
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:2iui
,
PDBe:2iui
,
PDBj:2iui
PDBsum
2iui
PubMed
8599763
UniProt
P27986
|P85A_HUMAN Phosphatidylinositol 3-kinase regulatory subunit alpha (Gene Name=PIK3R1)
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