Structure of PDB 2iic Chain A Binding Site BS01

Receptor Information

>2iic Chain A (length=302) Species: 5741 (Giardia intestinalis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

DAIPEVKAILEAKNEEELVTFTSRWSAEERKELRTQFQDTTGLEFIAFLK
KCIKNGPYEDVMALGWDCNISARVNVIKKAMKNVNDFRAIHDVVLIATPD
ERLKLAQAYKEKTGNDLLQDFVDQIPLTSAASYLCHLAIRENRTPRGSVA
SDAEVLKHNLIDADEPDHEAVVRLIITSTADEYKEINHRFEVLTGKSVQE
AIETRYADKENARGLCIAHYYNLAPARAVAYAFHSAVETQNDDMAYEQAA
RITGLFHDLHKFAWVHYACWGVMRDDILSRFQSKEANKVNFRDACLMFWK
LA

Ligand information

Ligand ID

InChI

InChI=1S/Ca/q+2

InChIKey

BHPQYMZQTOCNFJ-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Ca++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Ca+2]

Formula

Name

CALCIUM ION

PDB chain

2iic Chain A Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	2iic Apo and Calcium-bound Crystal Structures of Alpha-11 Giardin, an Unusual Annexin from Giardia lamblia
Resolution	2.93 Å
Binding residue (original residue number in PDB)	K53 K54 I56 K57 N58 E62
Binding residue (residue number reindexed from 1)	K50 K51 I53 K54 N55 E59
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0005509	calcium ion binding
GO:0005544	calcium-dependent phospholipid binding
GO:0046872	metal ion binding

	Biological Process
GO:0007010	cytoskeleton organization

	Cellular Component
GO:0005737	cytoplasm
GO:0005856	cytoskeleton
GO:0005874	microtubule

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Cellular Component

External links

PDB	RCSB:2iic, PDBe:2iic, PDBj:2iic
PDBsum	2iic
PubMed	17355882
UniProt	Q4VPP2

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