Structure of PDB 2icw Chain A Binding Site BS01

Receptor Information
>2icw Chain A (length=179) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFGRFA
SFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVELREP
NVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLP
FLPSTEDVYDCRVEHWGLDEPLLKHWEFD
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2icw Crystal structure of a complete ternary complex of TCR, superantigen and peptide-MHC.
Resolution2.41 Å
Binding residue
(original residue number in PDB)		Q9 I31 W43 A52 S53 F54 G58 N62 V65 D66 N69 R76
Binding residue
(residue number reindexed from 1)		Q7 I29 W41 A50 S51 F52 G56 N60 V63 D64 N67 R74
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

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Biological Process
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Cellular Component
External links
PDB RCSB:2icw, PDBe:2icw, PDBj:2icw
PDBsum2icw
PubMed17220897
UniProtP01903|DRA_HUMAN HLA class II histocompatibility antigen, DR alpha chain (Gene Name=HLA-DRA)

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