Structure of PDB 2hwn Chain A Binding Site BS01

Receptor Information
>2hwn Chain A (length=39) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IPPGLTELLQGYTVEVLRQQPPDLVDFAVEYFTRLREAR
Ligand information
>2hwn Chain E (length=19) Species: 9541 (Macaca fascicularis) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
EELAWKIAKMIVSDVMQQC
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2hwn A Dynamic Mechanism for AKAP Binding to RII Isoforms of cAMP-Dependent Protein Kinase.
Resolution1.6 Å
Binding residue
(original residue number in PDB)		I5 L13 Q14 T17 V18 L21 R22
Binding residue
(residue number reindexed from 1)		I1 L9 Q10 T13 V14 L17 R18
Enzymatic activity
Enzyme Commision number 2.7.11.11: cAMP-dependent protein kinase.
External links
PDB RCSB:2hwn, PDBe:2hwn, PDBj:2hwn
PDBsum2hwn
PubMed17081990
UniProtP12368|KAP2_RAT cAMP-dependent protein kinase type II-alpha regulatory subunit (Gene Name=Prkar2a)

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