Structure of PDB 2htx Chain A Binding Site BS01

Receptor Information
>2htx Chain A (length=129) Species: 9031 (Gallus gallus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KVFGRCELAAAMKRHGLDNYRGYSLGNWVCAAKFESNFNTQATNRNTDGS
TDYGILQINSRWWCNDGRTPGSRNLCNIPCSALLSSDITASVNCAKKIVS
DGNGMNAWVAWRNRCKGTDVQAWIRGCRL
Ligand information
Ligand ID220
InChIInChI=1S/C15H20O4/c16-10-3-1-2-6-14(12-18)7-4-8-15(13-19)9-5-11-17/h6,8,10-13H,1-5,7,9H2
InChIKeyWRPMDTWVLJJHMV-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341O=CCCCC=C(CC\C=C(\CCC=O)C=O)C=O
CACTVS 3.341O=CCCCC=C(CCC=C(CCC=O)C=O)C=O
OpenEye OEToolkits 1.5.0C(CC=C(CCC=C(CCC=O)C=O)C=O)CC=O
ACDLabs 10.04O=C\C(=C/CCCC=O)CC\C=C(\C=O)CCC=O
FormulaC15 H20 O4
NameUNDECA-3,7-DIENE-1,3,7,11-TETRACARBALDEHYDE
ChEMBL
DrugBankDB06912
ZINC
PDB chain2htx Chain A Residue 9130 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2htx Elucidation of the mechanism and end products of glutaraldehyde crosslinking reaction by X-ray structure analysis
Resolution1.56 Å
Binding residue
(original residue number in PDB)		K13 R128 L129
Binding residue
(residue number reindexed from 1)		K13 R128 L129
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) E35 N46 D48 S50 D52 N59
Catalytic site (residue number reindexed from 1) E35 N46 D48 S50 D52 N59
Enzyme Commision number 3.2.1.17: lysozyme.
Gene Ontology
Molecular Function
GO:0003796 lysozyme activity
GO:0005515 protein binding
GO:0016231 beta-N-acetylglucosaminidase activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
GO:0042802 identical protein binding
Biological Process
GO:0016998 cell wall macromolecule catabolic process
GO:0031640 killing of cells of another organism
GO:0042742 defense response to bacterium
GO:0050829 defense response to Gram-negative bacterium
GO:0050830 defense response to Gram-positive bacterium
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum

View graph for
Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2htx, PDBe:2htx, PDBj:2htx
PDBsum2htx
PubMed17461426
UniProtP00698|LYSC_CHICK Lysozyme C (Gene Name=LYZ)

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