Structure of PDB 2hgh Chain A Binding Site BS01

Receptor Information
>2hgh Chain A (length=87) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MYVCHFENCGKAFKKHNQLKVHQFSHTQQLPYECPHEGCDKRFSLPSRLK
RHEKVHAGYPCKKDDSCSFVGKTWTLYLKHVAECHQD
Ligand information
>2hgh Chain B (length=55) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gggccauaccucuugggccugguuaguaccucuucggugggaauaccagg
ugccc
<<<<....<<....>><<<<<<<.....<<........>>....>>>>>>
>>>>>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2hgh Induced Fit and 'Lock and Key' Recognition of 5 S RNA by Zinc Fingers of Transcription Factor IIIA
ResolutionN/A
Binding residue
(original residue number in PDB)
Y105 K117 K118 H119 N120 Q121 K123 K144 F146 L148 S150 R151 K153 R154 H155 V158 Y162 T176 W177 T178 K182
Binding residue
(residue number reindexed from 1)
Y2 K14 K15 H16 N17 Q18 K20 K41 F43 L45 S47 R48 K50 R51 H52 V55 Y59 T73 W74 T75 K79
Binding affinityPDBbind-CN: Kd=8nM
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:2hgh, PDBe:2hgh, PDBj:2hgh
PDBsum2hgh
PubMed16405997
UniProtP03001|TF3A_XENLA Transcription factor IIIA (Gene Name=gtf3a)

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