Structure of PDB 2h6p Chain A Binding Site BS01
Receptor Information
>2h6p Chain A (length=276) Species:
9606
(Homo sapiens) [
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GSHSMRYFYTAMSRPGRGEPRFIAVGYVDDTQFVRFDSDAASPRTEPRAP
WIEQEGPEYWDRNTQIFKTNTQTYRESLRNLRGYYNQSEAGSHIIQRMYG
CDLGPDGRLLRGHDQSAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAA
RVAEQLRAYLEGLCVEWLRRYLENGKETLQRADPPKTHVTHHPVSDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWEP
Ligand information
>2h6p Chain C (length=9) Species:
9606
(Homo sapiens) [
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KPIVVLHGY
Receptor-Ligand Complex Structure
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PDB
2h6p
Alloreactivity between disparate cognate and allogeneic pMHC-I complexes is the result of highly focused, peptide-dependent structural mimicry
Resolution
1.9 Å
Binding residue
(original residue number in PDB)
Y7 R62 N63 I66 T69 T73 S77 Y84 R97 Y99 S116 T143 K146 W147 A150 Q155 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 R62 N63 I66 T69 T73 S77 Y84 R97 Y99 S116 T143 K146 W147 A150 Q155 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:2h6p
,
PDBe:2h6p
,
PDBj:2h6p
PDBsum
2h6p
PubMed
16963442
UniProt
P01889
|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)
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