Structure of PDB 2h1j Chain A Binding Site BS01

Receptor Information
>2h1j Chain A (length=565) Species: 1422 (Geobacillus stearothermophilus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AMKFSEFRYERPDIAQLQASFQEALDSFRRAGSAALQHEAMKRINELRRR
YSTMANLCHIRHTIDTNDEFYKKEQDFFDETEPVVKGLVNDYYRALVSSP
FRAELEQVWGKQLFALAETQLKTYAPVIVEDLQKENKLASEYTKLIASAK
IMFEGEERTLAQLQPFVESPDRAMRQRASEARFSFFKDYEKELDELYDEL
VHVRTAIARKLGFQNFVELGYARLGRTDYNADMVAGYRRQVKTHIVPLAA
KLRERQRQRIQVEKLYYYDEPFMFPTGNPTPKGDADWIVQNGRQMYEELS
PETGEFFRYMVEHELMDLVAKKGKAGGGYCTYIDDYKAPFIFSNFTGTSG
DIDVLTHEAGHAFQVYESRHYDIPEYNWPTLEACEIHSMSMEFFTWPWME
LFFGEDADKYRFAHLSDALLFLPYGVAVDEFQHAVYENPDMTPAERKSVW
RNIEKAYLPTRDYADHDYLERGGFWQRQGHIYTDPFYYIDYTLAQVCAFQ
FWKRAQEDRASAWRDYVALCRLGGSRPFTELVKSANLQSPFADGAVASVV
GHIERWLDSVDDKAL
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain2h1j Chain A Residue 601 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2h1j Time-Controlled Microfluidic Seeding in nL-Volume Droplets To Separate Nucleation and Growth Stages of Protein Crystallization.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		H356 H360 E384
Binding residue
(residue number reindexed from 1)		H357 H361 E385
Annotation score4
Enzymatic activity
Enzyme Commision number 3.4.24.-
Gene Ontology
Molecular Function
GO:0004222 metalloendopeptidase activity
GO:0008237 metallopeptidase activity
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis
GO:0006518 peptide metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:2h1j, PDBe:2h1j, PDBj:2h1j
PDBsum2h1j
PubMed17099920
UniProtQ5L1D2

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