Structure of PDB 2gzm Chain A Binding Site BS01
Receptor Information
>2gzm Chain A (length=266) Species:
1392
(Bacillus anthracis) [
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KLNRAIGVIDSGVGGLTVAKELIRQLPKERIIYLGDTARCPYGPRSREEV
RQFTWEMTEHLLDLNIKMLVIACNTATAVVLEEMQKQLPIPVVGVIHPGS
RTALKVTNTYHVGIIGTIGTVKSGAYEEALKSINNRVMVESLACPPFVEL
VESGNFESEMAYEVVRETLQPLKNTDIDTLILGCTHYPILGPVIKQVMGD
KVQLISSGDETAREVSTILYHSKMLNEGEEQSDHLFLTTGKIGLFKEIAS
KWFGQPIENVKHIHLE
Ligand information
Ligand ID
DGL
InChI
InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m1/s1
InChIKey
WHUUTDBJXJRKMK-GSVOUGTGSA-N
SMILES
Software
SMILES
OpenEye OEToolkits 1.7.0
C(CC(=O)O)[C@H](C(=O)O)N
ACDLabs 12.01
O=C(O)C(N)CCC(=O)O
OpenEye OEToolkits 1.7.0
C(CC(=O)O)C(C(=O)O)N
CACTVS 3.370
N[C@H](CCC(O)=O)C(O)=O
CACTVS 3.370
N[CH](CCC(O)=O)C(O)=O
Formula
C5 H9 N O4
Name
D-GLUTAMIC ACID
ChEMBL
CHEMBL76232
DrugBank
DB02517
ZINC
ZINC000000895124
PDB chain
2gzm Chain A Residue 501 [
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Receptor-Ligand Complex Structure
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PDB
2gzm
Structural and functional analysis of two glutamate racemase isozymes from Bacillus anthracis and implications for inhibitor design.
Resolution
1.99 Å
Binding residue
(original residue number in PDB)
S12 P42 Y43 G44 C74 N75 T76 C185 T186 H187
Binding residue
(residue number reindexed from 1)
S11 P41 Y42 G43 C73 N74 T75 C184 T185 H186
Annotation score
5
Enzymatic activity
Catalytic site (original residue number in PDB)
D11 S12 C74 T76 T118 E153 C185 H187
Catalytic site (residue number reindexed from 1)
D10 S11 C73 T75 T117 E152 C184 H186
Enzyme Commision number
5.1.1.3
: glutamate racemase.
Gene Ontology
Molecular Function
GO:0008881
glutamate racemase activity
GO:0016853
isomerase activity
GO:0016855
racemase and epimerase activity, acting on amino acids and derivatives
GO:0036361
racemase activity, acting on amino acids and derivatives
Biological Process
GO:0008360
regulation of cell shape
GO:0009252
peptidoglycan biosynthetic process
GO:0071555
cell wall organization
View graph for
Molecular Function
View graph for
Biological Process
External links
PDB
RCSB:2gzm
,
PDBe:2gzm
,
PDBj:2gzm
PDBsum
2gzm
PubMed
17610893
UniProt
A0A6L8PKK6
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