Structure of PDB 2gyd Chain A Binding Site BS01

Receptor Information
>2gyd Chain A (length=168) Species: 9796 (Equus caballus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SQIRQNYSTEVEAAVNRLVNLYLRASYTYLSLGFYFDRDDVALEGVCHFF
RELAEEKREGAERLLKMQNQRGGRALFQDLQKPSQDEWGTTLDAMKAAIV
LEKSLNQALLDLHALGSAQADPHLCDFLESHFLDEEVKLIKKMGDHLTNI
QRLVQAGLGEYLFERLTL
Ligand information
Ligand IDDFE
InChIInChI=1S/C4H5F5O/c1-3(5,6)10-2-4(7,8)9/h2H2,1H3
InChIKeyLUGFHDZVRRASHY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.042-(1,1-difluoroethoxy)-1,1,1-trifluoroethane
CACTVS 3.341CC(F)(F)OCC(F)(F)F
OpenEye OEToolkits 1.5.0CC(OCC(F)(F)F)(F)F
FormulaC4 H5 F5 O
Name2-(1,1-DIFLUOROETHOXY)-1,1,1-TRIFLUOROETHANE
ChEMBL
DrugBank
ZINCZINC000008698362
PDB chain2gyd Chain A Residue 172 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2gyd Photoactive analogues of the haloether anesthetics provide high-resolution features from low-affinity interactions.
Resolution1.72 Å
Binding residue
(original residue number in PDB)		S27 Y28
Binding residue
(residue number reindexed from 1)		S26 Y27
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005506 iron ion binding
GO:0008198 ferrous iron binding
GO:0008199 ferric iron binding
GO:0046872 metal ion binding
Biological Process
GO:0006826 iron ion transport
GO:0006879 intracellular iron ion homeostasis
GO:0006880 intracellular sequestering of iron ion
Cellular Component
GO:0005737 cytoplasm
GO:0005764 lysosome
GO:0005776 autophagosome
GO:0031410 cytoplasmic vesicle
GO:0044754 autolysosome
GO:0070288 ferritin complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2gyd, PDBe:2gyd, PDBj:2gyd
PDBsum2gyd
PubMed17163775
UniProtP02791|FRIL_HORSE Ferritin light chain (Gene Name=FTL)

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