Structure of PDB 2gtw Chain A Binding Site BS01
Receptor Information
>2gtw Chain A (length=275) Species:
9606
(Homo sapiens) [
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GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGQEQRYTCHVQHEGLPKPLTLRWE
Ligand information
>2gtw Chain C (length=9) Species:
9606
(Homo sapiens) [
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LAGIGILTV
Receptor-Ligand Complex Structure
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PDB
2gtw
Structures of MART-1(26/27-35) Peptide/HLA-A2 Complexes Reveal a Remarkable Disconnect between Antigen Structural Homology and T Cell Recognition
Resolution
1.548 Å
Binding residue
(original residue number in PDB)
Y7 F9 E63 K66 H70 V76 D77 Y84 R97 Y99 Y116 T143 W147 V152 Q155 L156 Y159
Binding residue
(residue number reindexed from 1)
Y7 F9 E63 K66 H70 V76 D77 Y84 R97 Y99 Y116 T143 W147 V152 Q155 L156 Y159
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:2gtw
,
PDBe:2gtw
,
PDBj:2gtw
PDBsum
2gtw
PubMed
17719062
UniProt
P04439
|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)
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