Structure of PDB 2gpp Chain A Binding Site BS01
Receptor Information
>2gpp Chain A (length=225) Species:
9606
(Homo sapiens) [
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PYNKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGW
AKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIM
DEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHI
EDVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMTLPLLRQTSTKAV
QHFYNIKLEGKVPMHKLFLEMLEAK
Ligand information
>2gpp Chain C (length=11) Species:
9606
(Homo sapiens) [
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SLLLHLLKSQT
Receptor-Ligand Complex Structure
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PDB
2gpp
X-ray crystal structures of the estrogen-related receptor-gamma ligand binding domain in three functional states reveal the molecular basis of small molecule regulation.
Resolution
2.6 Å
Binding residue
(original residue number in PDB)
I280 K284 M298 E452
Binding residue
(residue number reindexed from 1)
I48 K52 M66 E220
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:2gpp
,
PDBe:2gpp
,
PDBj:2gpp
PDBsum
2gpp
PubMed
16990259
UniProt
P62508
|ERR3_HUMAN Estrogen-related receptor gamma (Gene Name=ESRRG)
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