Structure of PDB 2gpo Chain A Binding Site BS01
Receptor Information
>2gpo Chain A (length=224) Species:
9606
(Homo sapiens) [
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NKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAK
HIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIMDE
DQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIED
VEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMTLPLLRQTSTKAVQH
FYNIKLEGKVPMHKLFLEMLEAKV
Ligand information
>2gpo Chain C (length=10) Species:
9606
(Homo sapiens) [
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SLLLHLLKSQ
Receptor-Ligand Complex Structure
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PDB
2gpo
X-ray crystal structures of the estrogen-related receptor-gamma ligand binding domain in three functional states reveal the molecular basis of small molecule regulation.
Resolution
1.95 Å
Binding residue
(original residue number in PDB)
I280 K284 M298 L449 E452
Binding residue
(residue number reindexed from 1)
I46 K50 M64 L215 E218
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:2gpo
,
PDBe:2gpo
,
PDBj:2gpo
PDBsum
2gpo
PubMed
16990259
UniProt
P62508
|ERR3_HUMAN Estrogen-related receptor gamma (Gene Name=ESRRG)
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