Structure of PDB 2glf Chain A Binding Site BS01

Receptor Information

>2glf Chain A (length=450) Species: 2336 (Thermotoga maritima) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

KMERKNVWHHRKKEEIEAFSKEYMEFMSKAKTERMTVKEIKRILDESGFV
PLEDFAGDPMNMTVYAVNRGKAIAAFRVVDDLKRGLNLVVAHIDSPRLDF
KPNPLIEDEQIALFKTHYYGGIKKYHWLSIPLEIHGVLFKNDGTEIEIHI
GDKPEDPVFTIPDLLPHLDKEDAKISEKFKGENLMLIAGTIPLSGEEKEA
VKTNVLKILNEMYGITEEDFVSGEIEVVPAFSPREVGMDRSLIGAYGQDD
RICAYTALRALLSANPEKSIGVIFFDKEEIGSDGNTGAKARFYLKALRQI
LKMQGAKDSEFVLDEVLENTSVISGDVCAAVNPPYKDVHDLHNAPKLGYG
VALVKYTGARGKYSTNDAHAEFVARVRKVLNEQGVIWQVATLGKVDQGGG
GTIAKFFAERGSDVIDMGPALLGMHSPFEISSKADLFETYVAYRSLMEKL

Ligand information

Ligand ID

InChI

InChI=1S/Mn/q+2

InChIKey

WAEMQWOKJMHJLA-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mn+2]
CACTVS 3.341	[Mn++]

Formula

Name

MANGANESE (II) ION

PDB chain

2glf Chain A Residue 5001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	2glf Crystal structure of Aminipeptidase (M18 family) from Thermotoga Maritima
Resolution	2.8 Å
Binding residue (original residue number in PDB)	H94 D251 D328
Binding residue (residue number reindexed from 1)	H92 D249 D326
Annotation score	4

Enzymatic activity

Enzyme Commision number

3.4.11.-

Gene Ontology

	Molecular Function
GO:0004177	aminopeptidase activity
GO:0008237	metallopeptidase activity
GO:0008270	zinc ion binding
GO:0046872	metal ion binding

	Biological Process
GO:0006508	proteolysis

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Molecular Function

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Biological Process

External links

PDB	RCSB:2glf, PDBe:2glf, PDBj:2glf
PDBsum	2glf
PubMed
UniProt	Q9WYJ9\|APEA_THEMA Probable M18 family aminopeptidase 1 (Gene Name=apeA)

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