Structure of PDB 2gl7 Chain A Binding Site BS01

Receptor Information
>2gl7 Chain A (length=512) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EQDDAELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRS
PQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPALV
KMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNV
KFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTS
RVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDA
ATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQV
GGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEMAQNAVRLHYGL
PVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLV
RAHQDTQRFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFVQ
LLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGV
ATYAAAVLFRMS
Ligand information
>2gl7 Chain C (length=23) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
SQEQLEHRERSLQTLRDIQRMLF
Receptor-Ligand Complex Structure
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PDB2gl7 Crystal Structure of a beta-Catenin/BCL9/Tcf4 Complex.
Resolution2.6 Å
Binding residue
(original residue number in PDB)		L159 D162 D164 V166 M174
Binding residue
(residue number reindexed from 1)		L18 D21 D23 V25 M33
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0045296 cadherin binding
Biological Process
GO:0007155 cell adhesion

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Molecular Function
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Biological Process
External links
PDB RCSB:2gl7, PDBe:2gl7, PDBj:2gl7
PDBsum2gl7
PubMed17052462
UniProtP35222|CTNB1_HUMAN Catenin beta-1 (Gene Name=CTNNB1)

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