Structure of PDB 2gjw Chain A Binding Site BS01

Receptor Information
>2gjw Chain A (length=308) Species: 2234 (Archaeoglobus fulgidus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HHHHIGGDFAVVKAKKSLERRGFGVKRGDKIYLHPLEVVYLQIKGIESFG
ELEDVLSWAESRMEDFSTYYFVYEDLRDRGNKVKIQGEFLLTKKPYLPIS
ERKTIRMEEIAEKARNFDELRLAVVDEESEITYFRVYEPDMMGEQKEELP
EIAGVLSDEYVITKQTEIFSRYFYGSEKGDLVTLSLIESLYLLDLGKLNL
LNADREELVKRAREVERNFDRRYEVYRNLKERGFVVKTGFKFGSEFRVYR
KVESVDDLPHSEYLVDIADSREIRLIDLARAVRLAQNVRKRMVFAYGKNY
LCFERVKV
Ligand information
Receptor-Ligand Complex Structure
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PDB2gjw RNA Recognition and Cleavage by an Splicing Endonuclease
Resolution2.85 Å
Binding residue
(original residue number in PDB)		F173 F242 R247 Y249 L258 H260 S261 V288 K290
Binding residue
(residue number reindexed from 1)		F173 F242 R247 Y249 L258 H260 S261 V288 K290
Enzymatic activity
Catalytic site (original residue number in PDB) Y249 H260 K290
Catalytic site (residue number reindexed from 1) Y249 H260 K290
Enzyme Commision number 4.6.1.16: tRNA-intron lyase.
Gene Ontology
Molecular Function
GO:0000213 tRNA-intron endonuclease activity
GO:0003676 nucleic acid binding
GO:0016829 lyase activity
Biological Process
GO:0000379 tRNA-type intron splice site recognition and cleavage
GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation
GO:0008033 tRNA processing

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Molecular Function
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Biological Process
External links
PDB RCSB:2gjw, PDBe:2gjw, PDBj:2gjw
PDBsum2gjw
PubMed16690865
UniProtO29362|ENDA_ARCFU tRNA-splicing endonuclease (Gene Name=endA)

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