Structure of PDB 2gha Chain A Binding Site BS01

Receptor Information
>2gha Chain A (length=374) Species: 243274 (Thermotoga maritima MSB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MQPKLTIWCSEKQVDILQKLGEEFKAKYGVEVEVQYVNFQDIKSKFLTAA
PEGQGADIIVGAHDWVGELAVNGLIEPIPNFSDLKNFYETALNAFSYGGK
LYGIPYAMEAIALIYNKDYVPEPPKTMDELIEIAKQIDEEFGGEVRGFIT
SAAEFYYIAPFIFGYGGYVFKQTEKGLDVNDIGLANEGAIKGVKLLKRLV
DEGILDPSDNYQIMDSMFREGQAAMIINGPWAIKAYKDAGIDYGVAPIPD
LEPGVPARPFVGVQGFMVNAKSPNKLLAIEFLTSFIAKKETMYRIYLGDP
RLPSRKDVLELVKDNPDVVGFTLSAANGIPMPNVPQMAAVWAAMNDALNL
VVNGKATVEEALKNAVERIKAQIQ
Ligand information
Ligand IDGLC
InChIInChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1
InChIKeyWQZGKKKJIJFFOK-DVKNGEFBSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(C1C(C(C(C(O1)O)O)O)O)O
OpenEye OEToolkits 1.5.0C([C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O)O)O)O)O
CACTVS 3.341OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
CACTVS 3.341OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O
ACDLabs 10.04OC1C(O)C(OC(O)C1O)CO
FormulaC6 H12 O6
Namealpha-D-glucopyranose;
alpha-D-glucose;
D-glucose;
glucose
ChEMBLCHEMBL423707
DrugBank
ZINCZINC000003861213
PDB chain2gha Chain C Residue 1 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2gha T. maritima maltotriose binding protein
Resolution1.6 Å
Binding residue
(original residue number in PDB)		S12 E13 K14 F41 Q42 R303
Binding residue
(residue number reindexed from 1)		S10 E11 K12 F39 Q40 R301
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0015144 carbohydrate transmembrane transporter activity
GO:1901982 maltose binding
Biological Process
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0008643 carbohydrate transport
GO:0015768 maltose transport
GO:0034219 carbohydrate transmembrane transport
GO:0042956 maltodextrin transmembrane transport
Cellular Component
GO:0019773 proteasome core complex, alpha-subunit complex
GO:0055052 ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2gha, PDBe:2gha, PDBj:2gha
PDBsum2gha
PubMed
UniProtQ9X0T1

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