Structure of PDB 2g5o Chain A Binding Site BS01
Receptor Information
>2g5o Chain A (length=238) Species:
9606
(Homo sapiens) [
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NSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRE
LVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLL
FAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIIL
LNSGVYTFLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLI
LSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
Ligand information
>2g5o Chain C (length=10) Species:
9606
(Homo sapiens) [
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HKILHRLLQD
Receptor-Ligand Complex Structure
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PDB
2g5o
Human estrogen receptor alpha ligand-binding domain in complex with 2-(but-1-enyl)-17beta-estradiol and a glucocorticoid receptor interacting protein 1 NR BOX II Peptide
Resolution
2.3 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 V376 E380 E542
Binding residue
(residue number reindexed from 1)
I55 K59 L69 V73 E77 E232
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:2g5o
,
PDBe:2g5o
,
PDBj:2g5o
PDBsum
2g5o
PubMed
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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